Blood Sugar Is the Hidden Variable Behind Almost Everything You're Feeling.

The 3am wakeup. The afternoon crash. The mood that swings without warning. The weight that won't move. It may all be coming from the same place.

By Amanda, BSc Exercise Science | Prime Choice Club

Most of the symptoms people chalk up to stress, aging, poor sleep, or just not being a morning person, the 3am wakeup with heart racing, the energy crash at 2pm, the mood that turns dark out of nowhere, the stubborn weight that sits around the midsection regardless of how clean you eat, these are not separate problems with separate causes. They are different expressions of the same underlying issue: blood sugar instability.

Once you understand how blood glucose affects the stress response, the sleep cycle, neurotransmitter production, and the hormonal environment, you start seeing it everywhere. And once you address it properly, the downstream improvements can be remarkable.

BLOOD SUGAR IS NOT JUST A DIABETES CONVERSATION

First I want you to know that blood sugar dysregulation exists on a spectrum that has nothing to do with whether or not you have a diabetes diagnosis. Most people living with chronic energy fluctuations, poor sleep, mood instability, and stubborn weight are operating with subclinical blood sugar instability that never shows up as a problem on a standard fasting glucose test.

Here's what that can looks like. You eat a meal, blood sugar rises, insulin is released to shuttle glucose into cells, and blood sugar drops. If that drop is too fast or too steep, which happens with high-glycemic meals, inadequate protein and fat to slow absorption, or an already-stressed metabolic system, the body interprets the rapid decline as a threat. It activates the stress response and you feel hypoglycemic. Cortisol and adrenaline are released to mobilize stored glucose and bring blood sugar back up. You feel that as irritability, anxiety, fatigue, difficulty concentrating, or the sudden urgent need for something sweet. This is not hunger. This is a stress response triggered by metabolic instability.

Multiply that pattern across a day, add the overnight dimension we're about to get into, and you have a system under constant low-grade stress that shows up in your energy, mood, sleep, and body composition in ways that look like ten different problems but share a single root.

 

Why Blood Sugar Stability Matters

Blood sugar stability matters far beyond just avoiding a sugar crash. Your liver stores glycogen, which is your body's glucose reserves to keep blood sugar stable between meals and overnight. This is the key to buffering against the stress hormone cascade described above.

Here is how it works. Your brain and every cell in your body requires a continuous supply of glucose to function. Between meals and during sleep, that supply comes from liver glycogen: stored glucose that your liver releases steadily into the bloodstream to keep levels stable. The problem is that liver glycogen stores are limited, and when they run low, the body doesn't just wait patiently. It activates its emergency fuel mobilization system: cortisol and adrenaline surge to break down tissue and convert it to glucose, called gluconeogenesis. This keeps blood sugar from dropping dangerously but it also floods the system with stress hormones that are catabolic, inflammatory, and sleep-disrupting.

A different perspective to what most people think chronic low-grade stress, poor recovery, and energy instability is not primarily driven by psychological pressure but by metabolic instability: a liver that runs short on glycogen, triggering a cortisol response that the person experiences as anxiety, wakefulness, or fatigue but has no idea is metabolic in origin.

So here is how you can give your body what it needs so you can live on the preferred energy sources (glucose and thyroid hormones instead of stress hormones).  Eat enough easily digestible carbohydrates, including a small amount before bed, to keep the liver glycogen topped up through the night. But not enough that it will make you feel full so you don't mess with your body’s melatonin production. Fruit, fruit juices, raw honey, milk. Not to spike blood sugar but to sustain the glycogen reservoir that prevents the overnight stress cascade. Many people who implement this simple change report sleeping through the night for the first time in years.

THE 3AM WAKEUP EXPLAINED

This is the mechanism behind one of the most common and baffling sleep complaints: waking up between 2 and 4am feeling alert, sometimes with heart racing, unable to get back to sleep.

Your liver glycogen stores run low somewhere in the middle of the night, typically around the 4 to 6 hour mark depending on your diet and metabolic status. When they do, cortisol and adrenaline surge to mobilize glucose from other sources. That surge is effective at keeping your blood sugar from crashing, but it's also what pulls you out of deep sleep. Your heart rate climbs. Your mind activates. Your nervous system shifts from parasympathetic rest mode into sympathetic alert mode. And once that switch flips, getting back into deep sleep is very difficult because the stress hormones are still circulating.

This is not a sleep disorder. It's a metabolic event with a sleep consequence. Treating it with sleep aids misses the point entirely and typically makes the underlying blood sugar dysregulation worse over time by further suppressing the nighttime hormonal repair cycle.

The solution, from a nutritional standpoint, involves two things working together: keeping blood sugar stable through the evening and overnight so the liver never runs empty, and supporting the body's own blood sugar regulation mechanisms so the swings are smaller and the stress response is less easily triggered. This is exactly what a well-designed blood sugar support formula addresses.

You're Not You When You're Hungry.

Do you remember back In 2015, Snickers ran a Super Bowl commercial set inside The Brady Bunch. Marcia Brady gets hit in the nose with a football. She can't go to the dance. And instead of Maureen McCormick delivering her lines, it's Danny Trejo - wild-eyed, threatening "an eye for an eye" - until Carol hands her a Snickers and she returns to her normal self. It was funny because it was true. Snickers built a billion-dollar campaign on one biological fact: when your blood sugar drops, you are not yourself.

But nobody explained why. So here it is.

The mood connection is one an underappreciated dimension of blood sugar instability and could be your biggest clue you have a blood sugar stability issue.

Serotonin, the neurotransmitter most associated with mood stability, calm, and the sense that everything is basically okay, is synthesized from tryptophan. Tryptophan's entry into the brain is regulated by a transport mechanism that competes with other large neutral amino acids. Insulin, released in response to carbohydrate consumption, clears these competing amino acids from the blood, giving tryptophan preferential access to the brain and supporting serotonin synthesis. When blood sugar is unstable and insulin response is erratic, this tryptophan transport is also erratic, contributing to the mood volatility that tracks with energy instability.

Dopamine, the neurotransmitter for motivation, reward, and drive, is also sensitive to blood sugar status. The prefrontal cortex, which regulates emotional response, impulse control, and executive function, runs almost exclusively on glucose. When blood sugar drops, prefrontal function is among the first things to be impaired, which is why low blood sugar states produce irritability, poor decision-making, emotional reactivity, and difficulty moderating responses. You aren't overreacting. Your regulatory system is running on empty. You are, biologically speaking, Danny Trejo in a blonde wig.

Chronically unstable blood sugar creates a neurochemical environment where mood is inherently more volatile, emotional regulation is harder, and the baseline sense of wellbeing is lower. Stabilize the blood sugar and the mood often stabilizes with it, in a way that surprises people who thought they were dealing with a separate mental health issue.

BLOOD SUGAR, SLEEP, AND THE MELATONIN-INSULIN CONNECTION

Recent circadian biology research has added another dimension to the picture that I find fascinating, and it directly connects blood sugar management to sleep quality in a way that most people haven't heard.

Dr. Satchin Panda at the Salk Institute, one of the world's leading circadian biologists, has published extensively on the relationship between melatonin and insulin. The finding, now supported by human genetics research, is that the melatonin receptor gene MTNR1B is one of the strongest genetic predictors of type 2 diabetes risk. The mechanism: melatonin begins rising 2 to 3 hours before your natural bedtime as a signal that the day is ending. When melatonin binds to its receptor in the pancreatic beta cells, it tells them to reduce insulin secretion. The body is preparing for the overnight fast and downregulating the glucose management machinery.

The implication is significant. Eating carbohydrate-rich meals late at night, when melatonin is already rising and insulin secretion is being suppressed, means blood sugar stays elevated longer than it would earlier in the day because the hormonal machinery to handle it is being deliberately stood down. A 2023 randomized crossover trial found that late dinner timing was associated with 3.5-fold higher melatonin levels at mealtime, with significantly impaired insulin response compared to earlier eating. Panda's specific recommendation is to avoid carbohydrates and glucose within two hours of bedtime, allowing melatonin to rise into an insulin-stable environment.

The practical takeaway for blood sugar support is this: timing matters as much as composition. A blood sugar support formula helps your body manage glucose more effectively throughout the day, which means less erratic insulin response, fewer sharp drops, and a cleaner overnight fast that doesn't trigger the stress hormone cascade.

BLOOD SUGAR AND METABOLISM: THE WEIGHT CONNECTION

The metabolic consequences of blood sugar instability go well beyond how you feel in the moment. Chronically elevated insulin, which occurs when blood sugar is frequently and rapidly elevated, is the primary driver of fat storage, particularly visceral fat around the midsection. Insulin is a storage hormone: its job is to move glucose out of the bloodstream and into cells. When those cells are already full of glycogen and glucose, insulin directs the excess into fat tissue.

More problematically, chronic insulin elevation leads to insulin resistance, where cells become progressively less responsive to insulin's signal. This creates a feedback loop: blood sugar stays higher than it should, the pancreas produces more insulin to compensate, and the excess insulin drives more fat storage while simultaneously blocking fat release. People in this pattern can eat very little and still struggle to lose weight because the hormonal environment is blocking fat oxidation at the cellular level.

Dr Peat's framework adds another layer: chronic cortisol from blood sugar instability is itself directly lipogenic, promoting fat storage particularly in the abdominal region, and catabolic toward muscle tissue. The combination of elevated insulin and elevated cortisol that comes from unstable blood sugar is among the most powerful drivers of the body composition shift that most people over 35 recognize: gaining fat in the middle while losing muscle everywhere else, regardless of how hard they train.

Stabilizing blood sugar breaks this cycle. When glucose is managed smoothly, insulin stays in a healthy range, fat cells can release stored energy for fuel, and cortisol comes down from its chronic elevation. Body composition improves not because of caloric restriction but because the hormonal environment finally permits it.

EVERY INGREDIENT IN BLOOD SUGAR SMART AND WHAT IT'S DOING

This is a thoughtfully assembled formula covering five distinct mechanisms: insulin sensitivity support, glucose transport enhancement, antioxidant protection of pancreatic beta cells, cortisol and stress modulation, and the micronutrient cofactors that the glucose metabolism pathway depends on. Here is every ingredient:

Chromium (as Chromium AAC, 67mcg | 191% DV)
Chromium is the foundational mineral for insulin sensitivity and the most extensively researched micronutrient in blood sugar management. It is an essential component of chromodulin, a molecule that amplifies insulin receptor signaling, effectively making cells more responsive to insulin at lower concentrations. Research published in Diabetes Care has confirmed that chromium supplementation improves insulin sensitivity and glucose tolerance in people with insulin resistance and type 2 diabetes. At 191% of the daily value this formula is delivering a meaningful therapeutic dose of one of the most important blood sugar nutrients in existence.

Magnesium (as Magnesium Oxide, 125mg | 30% DV)
Magnesium is required for over 300 enzymatic reactions and plays a direct role in insulin signaling and glucose transport. Research published in Diabetes Care found that low magnesium levels are strongly associated with insulin resistance and that magnesium supplementation improves insulin sensitivity in both diabetic and non-diabetic populations. Magnesium also modulates the cortisol stress response, which is directly relevant given the blood sugar and cortisol feedback loop we discussed. Many people are chronically low in magnesium due to soil depletion and inadequate dietary intake, making supplementation particularly impactful.

Biotin (300mcg | 1000% DV)
Biotin is an essential cofactor for several carboxylase enzymes involved in glucose metabolism, specifically the enzymes that regulate gluconeogenesis (glucose production from non-glucose sources) and fatty acid synthesis. Research has shown that biotin deficiency impairs glucose utilization and that high-dose biotin supplementation can improve glucose metabolism in people with type 2 diabetes. At 1000% of the daily value this is a genuinely therapeutic dose targeting the enzymatic machinery of glucose handling directly.

Zinc (as Zinc Oxide, 8mg | 73% DV)
Zinc is essential for insulin synthesis, storage, and secretion in pancreatic beta cells. Insulin is stored in the pancreas as a zinc-insulin complex, and zinc deficiency directly impairs insulin production and release. Zinc also has antioxidant properties that protect beta cells from the oxidative stress that high blood sugar generates. Research published in Diabetologia has confirmed that zinc supplementation improves glycemic control and insulin secretion in people with type 2 diabetes.

Manganese (as Manganese AAC, 1mg | 43% DV)
Manganese is a cofactor for the enzyme manganese superoxide dismutase (MnSOD), the primary antioxidant enzyme in mitochondria. Beta cells in the pancreas have particularly high energy demands and are especially vulnerable to mitochondrial oxidative stress. Adequate manganese helps protect these cells from the cumulative damage that chronic blood sugar dysregulation produces. Manganese is also involved in carbohydrate metabolism directly as a cofactor for enzymes in the Krebs cycle.

Vitamin C (as Ascorbic Acid, 50mg | 56% DV)
Vitamin C is a potent antioxidant that protects pancreatic beta cells and vascular endothelium from the oxidative damage that elevated blood sugar generates. Research has shown that vitamin C competes with glucose for cellular uptake through the same transport mechanism, and adequate vitamin C status helps maintain antioxidant defenses even in high-glucose environments. It also supports adrenal function and cortisol regulation, directly relevant to the blood sugar and stress hormone feedback loop.

Vitamin E (as DL-Alpha Tocopheryl Acetate, 7mg | 47% DV)
Vitamin E protects cell membranes and low-density lipoproteins from the lipid peroxidation that elevated blood sugar and elevated insulin promote. Research has documented that people with insulin resistance and type 2 diabetes have significantly higher rates of oxidative stress, and vitamin E supplementation reduces these markers. In Peat's framework, vitamin E is also protective against the lipid peroxidation caused by polyunsaturated fats, which is directly relevant to the mitochondrial health that underlies efficient glucose metabolism.

Cinnamon Powder (Cinnamomum zeylanicum bark, 50mg)
Cinnamon is one of the most well-researched botanical ingredients for blood sugar management. A landmark randomized controlled trial published in Diabetes Care found that cinnamon supplementation significantly reduced fasting blood glucose, triglycerides, and LDL cholesterol in people with type 2 diabetes. Its primary mechanism involves compounds that mimic insulin signaling and improve glucose uptake by cells. It also activates the enzyme AMPK, which plays a central role in cellular glucose metabolism and energy sensing. As the highest-dosed botanical in this formula, cinnamon is doing significant work.

Alpha Lipoic Acid (30mg)
Alpha lipoic acid (ALA) is a unique antioxidant because it is both fat and water-soluble, meaning it can protect cellular structures in both environments where other antioxidants can only work in one. For blood sugar specifically, ALA has been shown in multiple clinical trials to improve insulin sensitivity, enhance glucose uptake in muscle cells, and reduce the oxidative stress markers associated with high blood sugar. Research published in Diabetes Care found that ALA supplementation significantly improved insulin-stimulated glucose disposal. It is also the primary treatment used in Europe for diabetic neuropathy, the nerve damage caused by chronic elevated blood sugar.

Bitter Melon Extract (Momordica charantia fruit, 20mg)
Bitter melon is one of the most studied anti-diabetic plants in traditional medicine systems across Asia, Africa, and South America, and the research has begun to validate its long history of use. It contains at least three compounds with hypoglycemic activity: charantin, vicine, and polypeptide-p, which appears to function similarly to insulin. Research published in the Journal of Nutritional Science and Vitaminology found that bitter melon extract significantly reduced blood glucose in diabetic subjects. It also activates AMPK, the same energy-sensing enzyme that metformin targets, making it one of the most pharmacologically relevant botanicals in this formula.

Banaba Extract (1% Corosolic Acid, Lagerstroemia speciosa leaf, 25mg)
Banaba leaf extract standardized to corosolic acid is one of the most compelling blood sugar botanicals to emerge from clinical research in recent years. Corosolic acid has been shown to stimulate glucose transport into cells by activating the GLUT4 glucose transporter, essentially mimicking one of insulin's key mechanisms without requiring insulin signaling. A double-blind placebo-controlled trial published in Diabetes Research and Clinical Practice found that banaba extract significantly reduced postprandial blood glucose spikes. It works quickly, with effects measurable within 60 minutes of consumption, making it particularly effective for managing the post-meal glucose rises that drive insulin dysregulation.

Gymnema Extract (Gymnema sylvestre leaf, 3mg)
Gymnema sylvestre has been used in Ayurvedic medicine for blood sugar management for over 2000 years and has a growing evidence base. Its active compounds, gymnemic acids, appear to block sweet taste receptors on the tongue and reduce glucose absorption in the intestine. Research published in the Journal of Ethnopharmacology found that Gymnema extract significantly reduced fasting blood glucose and HbA1c in both type 1 and type 2 diabetics over an 18 to 20 month period, with some subjects able to reduce medication. Its mechanisms include enhancing insulin secretion and supporting beta cell regeneration, making it one of the more comprehensive blood sugar botanicals available.

Guggul (Commiphora mukul resin, 50mg)
Guggul resin has a long history of use in Ayurvedic medicine and has been studied for its effects on lipid metabolism and insulin sensitivity. Its active compounds, guggulsterones, activate bile acid receptors and support liver function including the liver's role in glucose metabolism and glycogen storage. Research has documented guggul's effects on reducing elevated triglycerides and improving the lipid profile that typically accompanies insulin resistance. In the context of this formula it supports the liver metabolic health that is central to Ray Peat's framework for blood sugar stability.

White Mulberry Extract (Morus alba leaf, 3mg)
White mulberry leaf contains 1-deoxynojirimycin (DNJ), a potent inhibitor of alpha-glucosidase, the intestinal enzyme that breaks down complex carbohydrates into glucose. By slowing this breakdown, white mulberry extract reduces the rate at which glucose enters the bloodstream after meals, blunting the post-meal glucose spike and the insulin surge that follows. This is the same mechanism targeted by the prescription drug acarbose. Research has confirmed that white mulberry leaf extract significantly reduces postprandial blood glucose elevation.

Licorice Extract (Glycyrrhiza glabra root, 25mg)
Licorice root has multiple relevant mechanisms in a blood sugar support formula. Its active compound glycyrrhizin has been shown to improve insulin sensitivity by modulating the glucocorticoid receptor, directly relevant to the cortisol and blood sugar feedback loop. Research has also documented licorice's anti-inflammatory effects in the context of metabolic syndrome, addressing the chronic low-grade inflammation that both causes and is caused by blood sugar dysregulation. It also supports adrenal function, helping to normalize the cortisol output that unstable blood sugar chronically elevates.

Yarrow Powder (Achillea millefolium flower, 25mg)
Yarrow has documented effects on glucose metabolism and inflammation through its flavonoid content, particularly achillin and achillicin. Research has shown that yarrow extract reduces blood glucose in animal models of diabetes and has anti-inflammatory properties relevant to the metabolic inflammation that underlies insulin resistance. It also supports liver function, contributing to the hepatic glycogen management that Peat identified as central to blood sugar stability and stress hormone control.

Cayenne Pepper Powder (Capsicum annuum, 10mg)
Cayenne contains capsaicin, which has documented effects on glucose metabolism and energy expenditure. Capsaicin activates TRPV1 receptors that stimulate glucose uptake in skeletal muscle, improves insulin sensitivity, and has been shown in research to reduce postprandial blood glucose. It also has thermogenic effects that support overall metabolic rate and increases the efficiency of calorie burning from glucose. Research published in the British Journal of Nutrition found that capsaicin significantly improved glycemic control in subjects with insulin resistance.

Juniper Extract (Juniperus communis berry, 13mg)
Juniper berry has traditional use for metabolic support and recent research has begun to document its relevant mechanisms. Its active compounds include terpenes with anti-inflammatory and antioxidant activity relevant to the oxidative stress of blood sugar dysregulation. Research has documented hypoglycemic effects in animal models. In this formula it contributes to the overall anti-inflammatory and antioxidant protection of the metabolic environment.

L-Taurine (25mg)
Taurine is an amino acid with multiple relevant mechanisms in blood sugar management. Research published in Diabetes/Metabolism Research and Reviews found that taurine improves insulin sensitivity, supports pancreatic beta cell function, and reduces the oxidative stress associated with elevated blood sugar. Taurine also has cardiovascular protective effects that are particularly relevant given the connection between blood sugar dysregulation and cardiovascular risk. In Peat's framework, taurine is also relevant for its bile acid conjugation role, supporting the liver function that is central to glycogen metabolism and hormone clearance.

Vanadium (as Vanadyl Sulfate, 2mcg)
Vanadium compounds have been studied as insulin mimetics since the 1980s. Vanadyl sulfate has been shown in research to improve insulin sensitivity and reduce fasting blood glucose through mechanisms that partially bypass the insulin receptor, making it relevant even in conditions of significant insulin resistance. At the low dose used here it functions as a supportive trace mineral rather than a pharmacological intervention, contributing to the overall insulin sensitivity support of the formula.

THE FULL PICTURE: ONE FORMULA, FIVE MECHANISMS

What makes Blood Sugar Smart comprehensive rather than just having one or two headline ingredients is the way it addresses blood sugar dysregulation from five angles simultaneously.

The insulin sensitivity layer: Chromium, Magnesium, Alpha Lipoic Acid, Cinnamon, Cayenne, and Vanadium all support the cell's ability to respond appropriately to insulin, reducing the amount of insulin needed to manage a given glucose load and preventing the chronic hyperinsulinemia that drives fat storage and insulin resistance.

The glucose transport layer: Banaba (corosolic acid), Bitter Melon, and Gymnema all enhance glucose uptake into cells through mechanisms that work alongside or independent of insulin signaling, smoothing the glucose curve without requiring excessive insulin.

The intestinal glucose absorption layer: White Mulberry and Cinnamon slow the breakdown and absorption of glucose from the gut, reducing the height and speed of post-meal glucose spikes that trigger reactive insulin surges.

The antioxidant and beta cell protection layer: Alpha Lipoic Acid, Vitamin C, Vitamin E, Zinc, Manganese, and Taurine protect pancreatic beta cells and vascular tissue from the oxidative damage that chronically elevated blood sugar generates, preserving the body's own glucose management capacity over time.

The cortisol and liver support layer: Licorice, Guggul, Yarrow, and the B vitamin and mineral foundation support liver function, adrenal regulation, and the glycogen storage capacity that Peat identified as the central buffer against the overnight stress hormone cascade.

WHY PRIME CHOICE?

Prime Choice Sugar Smart is NSF Certified and GMP Certified, manufactured in the USA, and lab tested. In a supplement category where quality control is critical and where underdosed formulas are extremely common, independent certification is the only reliable assurance that what's on the label is in the capsule at the stated amount.

One capsule per day. Sixty servings per bottle. A formula that addresses the full complexity of blood sugar management rather than relying on a single ingredient. 

 

I've worked with clients for over two decades and the single most consistent finding I've come across is this: when blood sugar is unstable, everything else is harder. The training doesn't produce the results it should. The sleep doesn't restore the way it should. The mood is harder to manage. The weight doesn't move the way the effort warrants.

Fix the blood sugar and those things don't fix themselves automatically, but they become possible in a way they simply weren't before. It's the foundation. And foundations are always worth building first.

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2. Peat R. From PMS to Menopause. 1997. (cortisol, adrenaline, and nocturnal hypoglycemia)

3. Panda S. The Circadian Code. Rodale Books. 2019. (eating timing, melatonin, and insulin interaction)

4. Chang AM, Aeschbach D, Duffy JF, Czeisler CA. Evening use of light-emitting eReaders negatively affects sleep, circadian timing, and next-morning alertness. PNAS. 2015;112(4):1232-1237.

5. Zhu H, et al. The melatonin receptor 1B gene links circadian rhythms and type 2 diabetes mellitus. Annals of Medicine. 2023;55(1):1262-1286.

6. Leproult R, Van Cauter E. Role of sleep and sleep loss in hormonal release and metabolism. Endocrine Development. 2010;17:11-21.

7. Spiegel K, et al. Sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite. Annals of Internal Medicine. 2004;141(11):846-850.

8. Selye H. The Stress of Life. McGraw-Hill. 1956. (General Adaptation Syndrome and glucose mobilization)

9. Anderson RA. Chromium as an essential nutrient for humans. Regulatory Toxicology and Pharmacology. 1997;26(1 Pt 2):S35-41.

10. Broadhurst CL, Domenico P. Clinical studies on chromium picolinate supplementation in diabetes mellitus. Diabetes Technology and Therapeutics. 2006;8(6):677-687.

11. Grover JK, et al. Medicinal plants of India with anti-diabetic potential. Journal of Ethnopharmacology. 2002;81(1):81-100. (Bitter Melon, Gymnema, Banaba, Cinnamon)

12. Khan A, et al. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care. 2003;26(12):3215-3218.

13. Shanmugasundaram ER, et al. Use of Gymnema sylvestre leaf extract in the control of blood glucose in insulin-dependent diabetes mellitus. Journal of Ethnopharmacology. 1990;30(3):281-294.

14. Miura T, et al. Hypoglycemic activity of the fruit of the Momordica charantia in type 2 diabetic mice. Journal of Nutritional Science and Vitaminology. 2001;47(5):340-344.

15. Judy WV, et al. Antidiabetic activity of a standardized extract (Glucosol) from Lagerstroemia speciosa leaves in type II diabetics. Journal of Ethnopharmacology. 2003;87(1):115-117. (Banaba/Corosolic acid)

16. Packer L, et al. Alpha-lipoic acid as a biological antioxidant. Free Radical Biology and Medicine. 1995;19(2):227-250.

17. Ziegler D, et al. Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid. Diabetes Care. 1999;22(8):1296-1301.

18. Tiwari AK, Rao JM. Diabetes mellitus and multiple therapeutic approaches of phytochemicals: present status and prospects. Current Science. 2002;83(1):30-38. (White Mulberry, Licorice)

19. Bhavsar SK, et al. Vanadium compounds as insulin mimetics. Current Medicinal Chemistry. 2010;17(31):3594-3607.

20. Head KA. Natural approaches to prevention and treatment of infections of the lower urinary tract. Alternative Medicine Review. 2008. (Juniper berry)

21. Tapiero H, et al. Glucose and ROS in the pathogenesis of type 2 diabetes. Biomedicine and Pharmacotherapy. 2004. (Alpha lipoic acid, taurine, zinc in glucose metabolism)

22. Hansen SH. The role of taurine in diabetes and the development of diabetic complications. Diabetes/Metabolism Research and Reviews. 2001;17(5):330-346.

 

This is a sponsored advertorial. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Results may vary. Consult your healthcare provider before beginning any new supplement regimen, particularly if you are taking blood sugar medications, as some ingredients in this formula may enhance the effects of glucose-lowering drugs.